Below are screenshots from cavalierhealth.org about a benign condition in the Cavalier King Charles Spaniel that Cavalier and Cavapoo owners need to be aware of in order to prevent panic when routine blood tests are done (usually at the time of spaying and neutering) as a pre-check before surgery.  Not all vets know that it is considered "normal" for the Cavalier to have a low platelet count, or have very large platelets.  This does not affect the Cavalier or Cavapoo adversely and in most 90% of cases there is absolutely nothing wrong with your puppy.  To read the full article regarding this condition please follow the link: http://www.cavalierhealth.org/platelets.htm -- Thank you Cavalier Health for this info!